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Tag: TNF-α

Old man eye
Researchers publishing in Experimental Eye Research have discovered that the peptide aB-crystallin can reduce the cellular senescence that affects the progression of age-related macular degeneration (AMD). What is αB-crystallin? αB-crystallin is a well-known heat shock protein, a family of proteins that is used in temperature regulation. This protein has been previously demonstrated by this research...
Parkinson's
A study published in Cell Reports has found α-synuclein, the fundamental protein of Parkinson's disease, to be critical in immune function. The gut-brain axis as a channel for disease Parkinson's disease, which causes damage to the portion of the brain responsible for movement, is widely known to be caused by the aggregation of α-synuclein. This...
Spinal Injury
A team of researchers publishing in Aging have shown that resveratrol reduces inflammation and partially restores function in a rat model of spinal injury. In line with previous research This is far from the first study that aimed to use approaches associated with aging research in order to spur regeneration. For example, we have previously...
Storm
Research recently published in Aging shows how senescent cells overreact to inflammatory stimuli, causing them to excessively excrete compounds that promote inflammation. The researchers hypothesize that this is one cause of the cytokine storm, an immune overreaction that is more common in the elderly and is known to cause severe dysfunction and even death when...
Bosu exercise
A new study published in Aging Cell shows that a 12-week program of structured exercise lowers the activity of the inflammatory SASP in people in their mid-60s. Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are part;...
Antique, complicated clock
Researchers have developed a new transcriptomic aging clock that incorporates information about biological pathways. With this approach, the clock predicts not only age but also how the state of various genetic pathways changes with age, providing insight into the transcriptional changes involved in aging. Time for a new kind of clock In recent years, the...