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Tag: p53

Human Heart
Researchers have found that the protein fortilin, which is abundant in the heart, protects it from failure by blocking apoptotic activity. This discovery opens new possibilities in treating age-related heart diseases [1]. When your heart fails you As menacing at it sounds, heart failure (HF) does not mean that your heart has completely failed, just...
Antique, complicated clock
Researchers have developed a new transcriptomic aging clock that incorporates information about biological pathways. With this approach, the clock predicts not only age but also how the state of various genetic pathways changes with age, providing insight into the transcriptional changes involved in aging. Time for a new kind of clock In recent years, the...
In a recent study, researchers have explored senescence-related proteins and protein interactions in cataracts, a leading cause of visual impairment and blindness in older adults. Cataracts are characterized by the clouding of the lens in the eye, which leads to impaired vision. Cataracts generally develop slowly and can affect either one or both eyes at...
Scientists at the MRC Cancer Unit of the Wellcome Sanger Institute and other departments of the University of Cambridge discovered that healthy esophageal tissue accumulates very high numbers of mutations with age, to the point that, by the time middle age is reached, it is likely to contain more cells with a particular mutation than...