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Tag: Immunosenescence

July 03, 2019
Researchers from the Monash Biomedicine Discovery Institute have made progress in the quest to rejuvenate the aging immune system by identifying the factors responsible for the age-related decline of the thymus.  The thymus shrinks as we age The thymus is one of the most important organs in the body, and it is where thymocytes produced...
May 29, 2019
In a new study, researchers at the University of Pécs, Hungary used cell secretions known as exosomes to regenerate the thymus, one of the most important organs in the body. The thymus shrinks as we age The thymus is arguably one of the most critical organs in the body, and it is where new T...
March 26, 2019
A new review discusses how neutrophils release toxic substances into the body under inflammatory conditions, detailing one of the ways in which chronic inflammation causes long-term damage. Casting a deadly NET As we age, we suffer from the ever-increasing chronic inflammation known as inflammaging. This persistent, smoldering background of low-grade inflammation harms wound healing and...
March 19, 2019
Last year, resTORbio announced the positive results of its phase 2b human trial, which targeted the aging immune system with an immune system-boosting drug. Now, the company has announced the news that its therapy is moving to a phase 3 study later this year after successful negotiation with the FDA. Targeting the mTOR pathway of...
March 14, 2019
The March Journal Club hosted by Dr. Oliver Medvedik will focus on this recent study that showed transplanting the bone marrow of young laboratory mice into old mice prevented cognitive decline in the old mice, preserving their memory and learning abilities. These findings support the idea that cognitive decline is in part due to the aging of...
March 11, 2019
There is a strong correlation between the decline of the immune system and a decrease in future lifespan. As the immune system performs a myriad of functions with a multitude of specialized cell types, its breakdown has serious ramifications for health and longevity. As we age, our immune systems steadily decline, becoming less efficient and...