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Tag: CAR-T

Immunotherapy
In a pre-print paper, scientists have shown that treatment with NMN increases the survival and anti-cancer efficacy of CAR-T cells [1]. The problem with immunotherapy T cells are a central element of the adaptive immune system, and some of them can be cytotoxic: they have the ability to kill other cells. This lets us get...
Hosted by Dr. Oliver Medvedik, Journal Club returns on Tuesday 25th January at 12:00 Eastern and will be broadcast live on the Lifespan.io Facebook page. The topic for this month is the paper 'CAR T cells produced in vivo to treat cardiac injury', which looks at how researchers created CAR T cells to target scar...
Chest fibrosis
Scientists have created genetically engineered T cells that target activated cardiac fibroblasts in a transient manner, alleviating symptoms of cardiac injury [1]. HeartThe heart is a four-chambered organ located between our lungs. Blood is pumped by the heart through two loops, one to the lungs, oxygenating the blood, and the other out to the rest...
White blood cells
Could the immune system itself be the best way to purge senescent cells, which accumulate as we age, from the body? A new review takes a look at the role of the immune system in removing these problematic cells. What are senescent cells? As you age, increasing numbers of your cells enter into a state...