In the January Journal Club, we discussed the new drug J147 which targets mitochondrial dysfunction to potentially treat Alzheimer’s and other age-related diseases. We have also discussed the topic in an article last week if you wish to read about the progress being made with this drug.
Goldberg, J., Currais, A., Prior, M., Fischer, W., Chiruta, C., Ratliff, E., … & Cuezva, J. M. (2018). The mitochondrial ATP synthase is a shared drug target for aging and dementia. Aging cell.