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Interventions to Extend Healthspan and Lifespan 2018

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This spring happens to be rich with events promoting research on aging. Just one month after the Undoing Aging conference, jointly organized by the SENS Research Foundation and the Forever Healthy Foundation, we are expecting yet another visionary event in Kazan, Russia that might prove to be another great gift to our community.

Supervised by one of the most active proponents of aging research in Russia, RAS Correspondent Member Dr. Alexey Moskalev, the fifth international Interventions to Extend Healthspan and Lifespan conference will be held in Kazan on April 23-25, 2018.

The conference will gather brilliant scientists from all over the world in one place. To make it more comfortable for international guests, an English translation will be provided for all talks.

Here is an abstract from the program with the titles of the reports, offering a sense of how many important topics will be discussed.

Claudio Franceschi, University of Bologna, Italy



“Aging beyond chronological age: from Inflammaging to Immunobiography and Biological Age”

Jan Vijg, Albert Einstein College of Medicine, USA

“Integrated single-cell analysis of genome instability in aging”

Brian K. Kennedy, Yong Loo Lin School of Medicine, National University Singapore

“Preclinical to Clinical in Aging Research”



Alexey Moskalev, Institute of Biology of Russian Academy of Sciences, Syktyvkar, Russia

“Fucoxanthin as potential geroprotector”

Vadim Gladyshev, Harvard Medical School, USA

“Systems Biology of Aging and Longevity”

Jan Gruber, National University of Singapore



“Extension of healthspan by pharmacological interventions targeting ageing pathway synergies”

James Kirkland, Mayo Clinic, USA

“Cellular Senescence, Senolytics, Chronic Disease, and Aging”

Alexandra Stolzing, Vice President for Research, BioAge Labs

“Metabolomic biomarkers of human aging”



Mikhail Blagosklonny, Editor-in-Chief of the journals Aging and Oncotarget

“From rapalogs to anti-aging formula”

Stephen R Spindler, University of California, Riverside, USA

“Flies, mice and humans, and a search for longevity therapeutics”

Vera Gorbunova, Rochester University, USA



“Activation of transposable elements – a driver of age-related disease”

Joao Pedro De Magalhaes, PhD Institute of Ageing and Chronic Disease University of Liverpool

“Drugs, genes and databases”

Blanka Rogina, Editor-in-Chief of the journal Frontiers in genetics of Aging, USA

“The role of INDY in Metabolism, Health and Longevity”



This list is not exhaustive; feel free to check the full 3-day program here.

This conference will also hold three roundtables, covering theoretical aspects of aging research (programmed aging), practical approaches to active longevity, and my favorite topic – approaches to inform the general public about longevity technologies. I am going to give a talk to shed light on the best messaging to make the topic more accepted by the audience as well as certain aspects of interaction between academia, science popularizers, representatives of the mass media, and the general public.

Of course, as a LEAF representative, I will also use the opportunity to interview the leading researchers of aging in order to keep our readers updated on their work. However, if you know a longevity-friendly journalist, it makes perfect sense to let them know of this wonderful conference. Remember, when a large mass media company popularizes what is going on in the field of rejuvenation research, millions of people get informed, and eventually, they could become new members of our movement.

The conference venue is the Korston Royal Kazan hotel (1A Ershova street, Kazan), which is located close to the ancient heart of the city. I have been to Kazan before to give a talk about the advancement of rejuvenation research, and I am most confident that this city will charm you with its unique beauty and mix of cultural influences. I hope to see you there in April!

The official press release of the conference is provided below.



Interventions to Extend Healthspan and Lifespan International Conference

The fifth Interventions to Extend Healthspan and Lifespan international conference will be held in Kazan on April 23-25, 2018. Scientists, heads of medical companies, experts, and leading researchers from 17 countries all over the world will discuss opportunities for increasing life expectancy and maintaining healthy, active longevity. The first conference was held 10 years ago, and since then, with every passing year, the event is becoming more and more relevant while attracting new participants. The event is organized by Initiium-Pharm LLC with the support of the Tatarstan Investment Development Agency. The event is conducted under the scientific supervision of Alexey Moskalev, Correspondent Member of RAS, Ph.D. of Biological Sciences.

Such issues as the impact of environmental factors on aging processes, genetic mechanisms of longevity, pharmacological interventions, and aging biomarkers are among the key topics of the conference.

Although human aging is one of the most complicated biological processes, it determines human life quality and expectancy. In Europe, between the 19th century and the beginning of the 21st century, the average life expectancy has risen from 40 years to 81 for women and from 35 years to 79 for men. It is growing steadily by three years per decade. The elderly population has grown, which means that the rates of socially significant chronic diseases, such as cardiovascular diseases, oncologic diseases, Type 2 diabetes, arterial hypertension, and osteoporosis have risen as well. The prosperity of older people and the effectiveness of health and social protection systems depend on the development and implementation of experimental approaches that could slow down or reverse the aging process. This part of biomedicine is closely intertwined with the future concept of 4P medicine (predictive, preventive, personalized and participatory). Matters related to the genetic and epigenetic mechanisms of aging, geroprotective interventions, and aging and longevity biomarkers that help to estimate the effectiveness of treatment will be addressed at the international conference. Also, the experts will discuss how environmental factors affect the aging process itself.



The Republic of Tatarstan is a rapidly developing region of the Russian Federation, with an average life expectancy of 73 years. While it might not be the highest rate of the world, Tatarstan is traditionally ranked in the top 10 regions of Russia for life expectancy. Positive dynamics and growth of this indicator have been noted in recent years. A high standard of living, the progressive improvement of the local ecological situation, active lifestyles and widespread physical training throughout Tatarstan have contributed to this.

A plenary session of the conference will be moderated by the Russian journalist and TV presenter Boris Korchevnikov.

The conference is a platform where leading scientists and world-famous specialists from 30 top-ranked universities of 17 countries all over the world will present the latest research results in various fields, discuss perspectives, implementation trends and commercialized opportunities, and establish essential contacts and partnerships. Such worldwide experts as James Kirkland, a specialist at Mayo Clinic (USA), Claudio Franceschi, a professor and employee of the Department of Experimental Pathology of the University of Bologna (Italy), Brian K. Kennedy, a professor of the National University of Singapore, Dario Riccardo Valenzano, and many other specialists have already confirmed their participation in the conference.

“This conference will give a unique opportunity to join forces of prominent scientists, science popularizers and people who can share the secrets of their bright and active lives at a mature age,” said Faniya Maganova, Co-chair of the Organizing Committee and the head of Initium-Pharm, a pharmaceutical company. “It will let us break the stereotypes about aging, which is seen as something frightening and irreversible. Our main goal is to teach people how to welcome aging with pleasure and make the knowledge about the secrets of a long and active life available to everybody.”

According to Alexey Moskalev, Ph.D. of Biological Sciences, Co-chair of the Organizing Committee and Correspondent Member of RAS, the aim of the conference is to review breakthrough successes in the field of prolonging healthy lifespans, to report scientifically proven approaches to slowing aging, and to introduce the causes of this phenomenon and ways to assess its speed and correction to the general scientific and medical community, government authorities, business representatives, and interested citizens.



Welcome to healthy and active Tatarstan!

About Initium-Pharm

Initium-Pharm LLC (Limited Liability Company) is a research and production company engaged in the development, introduction and manufacture of medical and parapharmaceutical products. The company was established with the purpose of finding new pharmaceutical compositions that could have significant therapeutic and preventive effects while demonstrating minimal side effects and toxicity. In order to achieve this, its scientific research focuses mainly on the study of terpenes, as they are the most promising natural substances that possess a wide range of pharmacologically significant biological properties.

Contacts:

Press Attache of the Conference



Natalia Kuchumova

8 (843) 570 40 01 (1317)

[email protected]

www.extendlifespan2018.org

About the author

Elena Milova

Elena has been a longevity activist and advocate since 2013, when she first started to organize educational events to make new evidence-based methods of healthy life extension more popular. The last few years have seen Elena leading some successful projects in Russia, aimed at spreading the idea of healthy longevity among decision makers as well as the general public. Several years of lobbying resulted in the inclusion of her propositions in the strategic program documents of the Russian Federation related to the problems of the elderly. She is a co-author of the book “Aging Prevention for All” (in Russian, 2015), where, among other topics, she is sharing how to facilitate the adoption of the healthy lifestyle to promote the period of good health. In 2015, Elena helped to shape and coordinate the successful crowdfunding campaign of the Major Mouse Testing Program – a study of Senolytic drug combinations on mouse lifespan. In 2017 at LEAF, Elena led a successful advocacy project to include the problems of the elderly into the WHO’s 13th Programme of Work . Previously Elena has worked as a project manager in the pharmaceutical and advertisement industries, helping to promote new drugs and therapies. This experience helped her to realize that the existing therapies were not 100% effective and could not completely stop age-related diseases – which has ignited an interest for the development of innovative therapies. Elena graduated with a bachelor’s in both psychology and foreign languages and is now working to earn her MBA at the oldest Russian business school MIRBIS.
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