At Ending Age-Related Diseases 2020, Gabriela Bunu of the Institute of Biochemistry, Romanian Academy discussed SynergyAge, a database of the interactions of longevity-associated genes. This database is designed to calculate which genes are responsible for longevity, and which genes have been associated with a lack of longevity, in several distinct organisms, including mice. Multiple biochemical pathways were addressed, including the mTOR pathway and autophagy. Most notably, many of these genes had a synergistic effect, showing the combinations of expressed proteins that are most fruitful in extending lifespan.
Gabriela Bunu on Longevity Genes at EARD2020
This curated database shows the synergistic interactions between these genes.

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