Gabriela Bunu on Longevity Genes at EARD2020

At Ending Age-Related Diseases 2020, Gabriela Bunu of the Institute of Biochemistry, Romanian Academy discussed SynergyAge, a database of the interactions of longevity-associated genes. This database is designed to calculate which genes are responsible for longevity, and which genes have been associated with a lack of longevity, in several distinct organisms, including mice. Multiple biochemical pathways were addressed, including the mTOR pathway and autophagy. Most notably, many of these genes had a synergistic effect, showing the combinations of expressed proteins that are most fruitful in extending lifespan.