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Month: May 2021

Elderly woman drinking alcohol
A study funded by the National Institutes of Health has found that excessive alcohol consumption increases the epigenetic age of non-Hispanic White women according to the GrimAge epigenetic clock. Why we Age: Epigenetic AlterationsEpigenetic alterations are age-related changes in gene expression that harm the fundamental functions of cells and increase the risk of cancer and...
AKG may be a useful supplement for slowing down aging.
Alpha-ketoglutarate (AKG) has long been a popular sports supplement and is often used in the bodybuilding world, but interest in this molecule has now reached the aging research field due to its central role in metabolism. What is alpha-ketoglutarate? AKG is a naturally occurring endogenous intermediary metabolite and part of the Krebs cycle, which means...
Facebook Post Announce
The #1 Event for Rejuvenation Biotechnology and Life Extension We at Lifespan.io are excited to announce our fourth annual Ending Age-Related Diseases Conference, EARD2021. The conference will take place virtually on August 19-22, 2021 and will focus on four traditional themes: the mechanisms of aging, rejuvenation human trials, biomarkers of aging, and investment matters. We...
Elderly Man on Pullup Bar
In a new paper published in Nature, a group of scientists led by Peter Fedichev explores human longevity through the concept of loss of resilience, by which the researchers mean the gradual age-related expansion of time that the body needs to recover from stress, such as illness. According to the findings, this progressive loss of...
PEARL AMA
Today, we want to announce we are doing an AMA on Reddit Futurology! The Ask Me Anything thread will be open May 28 and 29 for pre-questions, and on May 30 and 31, the PEARL team will be answering questions. This is your opportunity to ask questions about the project, which aims to launch human...
RNA strand
New research has identified a set of long noncoding RNAs involved in inflammaging and the senescence-associated secretory phenotype (SASP) [1]. These RNAs are conserved across a range of species, including humans, and may prove a valuable avenue for controlling senescence. Age-related RNAs RNA can broadly be divided into protein-coding RNAs and noncoding RNAs, which have...

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