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Month: October 2019

It has been a while since the last update from MMTP, so we wanted to let you know how things are progressing.  As we explained in the last update, the internal review board (IRB) has concerns and further questions relating to the ethics of life extension and lifespan studies, and we are continuing to try...
Mitomouse
With just 15 days for the MitoMouse project fundraiser left, we thought it would be the ideal time to share with you some questions we asked the team about the project. To kick things off we have Dr. Matthew O’Connor the Vice President of Research at the SENS Research Foundation talking about the the MitoSENS program at...
Ronald Kohanski Interview
It was a pleasure speaking to Dr. Ronald Kohanski at the 2019 Ending Age-Related Diseases conference. Dr. Kohanski joined the field of aging research in 2005 as a Program Officer for the Division of Aging Biology at the National Institute on Aging. He moved on to become its Deputy Director in 2007 and has held...
double strand break
A team of researchers, including Dr. David Sinclair, has recently made a new study available as a preprint prior to peer review and publication in the journal Cell. DNA damage and the double-strand break Two of the primary hallmarks of aging are genomic instability, which consists of damage to our DNA, and epigenetic alterations, which...
Eye
GenSight Biologics has recently released data showing the effectiveness of GS010, the company's gene therapy for Leber Hereditary Optic Neuropathy (LHON), a mitochondrial disease that can lead to blindness. Like in previous studies, this therapy had a bilateral effect. Gene Therapy In LHON, the mitochondrial protein ND4 is poorly expressed through mitochondrial DNA (mtDNA). GS010...
Mitochondria
Back in January, we were joined by Dr. Aubrey de Grey, Dr. Amutha Boominathan, Dr. Matthew O'Conner, and Michael Rae from the SENS Research Foundation for a webinar discussion panel focused on MitoSENS, the mitochondrial repair program. During the webinar, a number of points were discussed, and the Lifespan Heroes in the audience got to...

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