June 29, 2018
Today we are pleased to announce that UNITY Biotechnology is going into human clinical trials with the first true rejuvenation therapy that directly targets one of the processes of aging: senescent cells. The quiet revolution In our collective imagination, revolutions start with a bang; however, more often than not, real-life technological revolutions start quietly and...
June 28, 2018
After meeting him at the Astana Global Challenges Summit 2018, we've kindly been granted an interview by Dr. Anthony Atala, M.D., Director of the Wake Forest Institute for Regenerative Medicine and the W. Boyce Professor and Chair of Urology at Wake Forest University. Dr. Atala is one of the most influential names in the field...
June 27, 2018
Today, we conclude our two-part interview with Dr. Michael Fossel, you can find part one here. Changing tack a bit here, you talk a little bit in your book about programmed human death; we're basically programmed to die through evolution's weird workings and you kind of flesh out what Josh Mitteldorf calls the demographic theory...
June 26, 2018
Today, we have part one of a two-part interview with Dr. Michael Fossel, the driving force behind Telocyte, a new company focused on telomerase therapy for various diseases, and a strong advocate of telomerase therapy to treat human disease over the past three decades. You can find part two of the interview here. I interviewed...
June 25, 2018
According to scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, or DKFZ), the enzyme TXNIP, which inhibits the enzyme TRX-1, might be a regulator of aging and might be a viable candidate for future interventions against age-related diseases [1]. Study summary The “free radical theory of aging” suggests that reactive oxygen species (ROS) are...
June 21, 2018
We have recently had occasion to have a chat with Dr. Vadim Gladyshev, Professor of Medicine and Director of Redox Medicine at Brigham and Women’s Hospital, Harvard Medical School, in Boston, Massachusetts. He is an expert in aging and redox biology and is known for his characterization of the human selenoproteome. His research laboratory focuses...