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Search Results for: Oisin

June 05, 2020
Don’t let your birthday get you down and remind you that you are getting older; there are plenty of reasons to be cheerful about the future and your place in it, especially as science is now turning its attention to aging. Another trip around the sun So here I am again, another birthday just gone...
February 26, 2020
I grew up in northern Sweden, and from early childhood, I always had a general interest in all kinds of science and technology. I often thought about the future and what sort of society we would evolve into. As far as my memory goes, back even when I was only 3-4 years old, I enjoyed...
February 07, 2020
Let’s face it, getting older sucks, and not because of all the extra candles on the birthday cake. Getting cake and presents every year is great, but the loss of health and independence isn't a particularly good birthday present. (Wow, what'd I get this year? Just what I didn't want: sarcopenia and hearing loss!) Given...
November 14, 2019
Today, Underdog Pharma, a spin-off company of SENS Research Foundation, was officially launched with the lofty goal of eradicating atherosclerosis. Atherosclerosis is the leading cause of death worldwide and currently has no effective solution. Current medicine has three broad approaches towards it: lifestyle changes, such as diet and exercise; drugs that reduce the accumulation of...
October 22, 2019
We're continuing to release talks from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology. John Lewis of Oisin Biotechnologies discussed senolytics, which are drugs that kill senescent cells. He explained the differences between healthy...
April 05, 2019
At the Undoing Aging 2019 conference, we had the opportunity to interview Yuri Deigin, the CEO of Youthereum Genetics. His company is developing therapies that focus on OSKM, the Yamanaka factors known for turning cells back into a pluripotent state. By partially reprogramming cells using a single component of OSKM, Oct4, the company hopes to...
April 04, 2019
We recently attended the Undoing Aging Conference in Berlin and had the opportunity to interview Professor Vittorio Sebastiano of Turn.Bio, a company developing partial cellular reprogramming techniques to reverse cellular aging. As we age, our cells experience changes to their epigenetic markers, and this, in turn, changes gene expression, which is proposed to be a...
April 02, 2019
The day after I got back from the Undoing Aging 2019 scientific conference, which was jointly organized by the SENS Research Foundation and Forever Healthy Foundation, Moscow greeted me with the first sunny days of the spring. Still tired and lacking sleep, but happy and inspired, I want to share my impressions of this year’s...
March 20, 2019
We have talked about the potential of partial cellular reprogramming in previous articles, and today, we want to draw attention to a new paper that promises to further refine reversal of epigenetic aging in cells. As we age, our cells experience alterations to their epigenetic markers, and this changes gene expression, which is proposed to...
February 22, 2019
July 2019 will see the launch of our second Ending Age-Related Diseases conference at the Frederick P. Rose Auditorium, Cooper Union in New York City. The event was so popular last year that we decided to expand it to two full days of science and biotech business this year. We will be bringing you the...
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March 23, 2019
You can download a copy of the event abstracts booklet here should you wish to do so. Day 1, Thursday, July 11th 8:00 - 9:00  Registration, Networking 9:00 - 9:10  Welcome talk by LEAF President Keith Comito 9:10 - 9:15  Welcome from Maurice Kanbar Center for Biomedical Engineering Director Oliver Medvedik 9:15 - 9:45 Opening...
April 04, 2018
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Fight Aging!
April 23, 2020
This short interview with Gary Hudson of Oisin Biotechnologies (and more recently Turn.bio) covers some of the history and the present status of the company and its spinoff OncoSenX. Oisin Biotechnologies is one of the more ambitious senolytics companies working on means of destroying senescent cells in old tissues in order to produce rejuvenation. The...
Fight Aging!
October 18, 2019
This article includes a brief history of how the senolytic suicide gene therapy company Oisin Biotechnologies came about. Oisin Biotechnologies was one of the first senolytics biotech startups, of which there are now many, one of the first longevity industry companies, and launched at a time in which it was still quite hard to persuade...
OncoSenX Raises $3 Million to Adapt the Oisin Biotechnologies Platform to Cancer
July 10, 2019
Oisin Biotechnologies uses a form of programmable suicide gene therapy to target senescent cells for destruction. The therapy can be triggered by expression of specific genes inside a cell, and so beyond senescent cells there is a long, long list of possibly harmful cell populations in aging and disease that it would be beneficial to...
OncoSenX is the Oisin Biotechnologies Spinoff Targeting Cancer
July 26, 2018
26 Jul 2018 26Jul2018 OncoSenX is the Oisin Biotechnologies Spinoff Targeting Cancer Loading... Loading... Oisin Biotechnologies developers a programmable suicide gene therapy platform, initially used to clear senescent cells from old tissues and thereby produce rejuvenation. Since this approach can also be directed to kill cancerous cells, and with little alteration to the original details...
Oisin Biotechnologies Produces Impressive Mouse Life Span Data from an Ongoing Study of Senescent Cell Clearance
July 17, 2018
17 Jul 2018 17Jul2018 Oisin Biotechnologies Produces Impressive Mouse Life Span Data from an Ongoing Study of Senescent Cell Clearance Loading... Loading... Oisin Biotechnologies is the company working on what is, to my eyes, the best of the best when it comes to the current crop of senolytic technologies, approaches capable of selectively destroying senescent...
Fight Aging!
June 04, 2018
Oisin Biotechnologies is one of a number of companies to have emerged from our community in recent years, from the network of supporters and researchers connected to the Methuselah Foundation and SENS Research Foundation. The Oisin principals are working with a platform capable of selectively destroying cells based on the internal expression of specific proteins....
Fight Aging!
March 29, 2018
This recent interview with Gary Hudson of Oisin Biotechnologies covers a range of topics; there is a lot more to it than is quoted here. The company is working on the application of a programmable gene therapy to the targeted destruction of senescent and cancerous cells. Since the approach can be adjusted to kill cells...
Fight Aging!
May 22, 2020
Kingsley Advani is one of the more active angel investors in the growing longevity industry. This is still a young industry, and like many of people involved, whether as entrepreneurs or investors, Advani is motivated more by an interest in achieving progress in medical technology than in a return on investment. Though of course, investors...
More Data on the Tissue Specificity of Senescent Cell Accumulation with Age in Mice
February 06, 2020
As work progresses on the clinical development of senolytic therapies to selectively destroy harmful senescent cells in old tissues, it is becoming ever more necessary to have a better understanding of just how many senescent cells are present in any given tissue with age. Not all tissues acquire lingering populations of these cells at the...
Against Senolytics
November 19, 2019
There is no consensus in science that is so strong as to have no heretics. So here we have an interview with a naysayer on the matter of senolytic treatments, who argues that the loss of senescent cells in aged tissues will cause more harm to long-term health than the damage they will do by...