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Hevolution
Hevolution announced its investment of $20 million (SAR 75,000,000) as the lead investor for a $50 million (SAR 188,000,000) Series A financing extension in Aeovian Pharmaceuticals. Hevolution’s investment will advance promising therapies that target the mTORC1 biological pathway, helping find solutions to major unmet medical needs including neurological diseases and other diseases of aging. Hevolution’s...
Mouse measurement
In Aging, researchers have published negative results on the long-term use of methylene blue and mitoquinone (MitoQ), two popular antioxidants, to sustain bone health in mice. Oxidative stress and bone health Previous work has found that oxidative stress, which is commonly associated with age-related disease and damage, is related to bone diseases. Substantial amounts of...
Long peppers
Scientific Reports has published a study that used a computational approach to identify natural senotherapeutics that have a similar impact on gene expression as a known senotherapeutic drug, dasatinib [1]. Drug combinations for better treatments Cellular senescence, a state in which cells cannot divide anymore but are still metabolically active and often display senescence-associated secretory...
Pig
After a total of 69 rejection-preventing gene edits, history has been made with the first-ever successful transplantation of a pig kidney into a human patient. Xenotransplantation within reach Organ transplantation has been one of modern medicine’s biggest triumphs, helping to save innumerable lives. It is also viewed as one of the pathways to life extension....
Obesity measurement
According to a paper published in Aging, a fisetin derivative that is being investigated for brain protection may also be effective in controlling glucose and ameliorating obesity. Repurposing a repurposed compound CMS121, the focus of this study, was created by modifying fisetin, a flavonol that is well known for its effects against cellular senescence. CMS121...
Oligodendrocytes
In Cell, researchers have published a paper outlining the different ways in which brain cells slowly mutate with aging. The genomic damage of aging Cells accumulate mutations with aging, including brain cells [1]. However, as these researchers note, most previous research into these mutations has been on neurons rather than the glia, the helper cells...
David Sinclair Interview
In this new interview, David Sinclair, Harvard professor and the author of “Lifespan”, explains his theory of aging, shares parts of his health routine, and reveals which directions in today’s aging research excite him. A professor and a public figure In the longevity field, when it comes to name recognition, there’s David Sinclair and all...
ARDD2024
According to the United Nations, the proportion of people aged over 65 now outnumber children younger than 5. The enormous growth in the elderly population is posing a socioeconomic challenge to societies worldwide, and necessitates new sweeping interventions for age-associated diseases. This year we have an incredibly exciting program with global thought-leaders sharing their latest...
Astrocytes
In an in-depth paper in Nature, researchers have explained how astrocytes, helper cells that provide crucial brain functions, epigenetically remember things in a way that encourages inflammation. Traumatized cells Long-lived immune cells, including T cells and B cells, can remember foreign pathogens [1]. This is why people can become immune to diseases after catching them...
Editorial
Spring is in the air if you are in the Northern Hemisphere, and in the theme of new growth, let’s see what the Lifespan.io team has been up to recently. Happy Birthday to Lifespan.io Today, March 21st, it is our birthday, and we celebrate 10 years of supporting rejuvenation research. Lifespan.io President Keith Comito said,...
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Sponsor A Combinatorial Intervention $200.00 Sponsor A Combinatorial Intervention Dropdown AbacavirAbacavir sulfateABC294640AbirateroneAbiraterone acetate - SponsoredAbscisic Acid (Dormin)ABT 702 dihydrochlorideABT-199ABT-263 (Navitoclax)-SPONSOREDABT-737ABT-751 (E7010)ABT-888 (Veliparib)AC480 (BMS-599626)Acalisib (GS-9820) Acamprosate calciumAcarbose - SponsoredAcebutolol HClAcemetacinAcesulfame PotassiumAcetaminophenAcetanilideAcetate gossypolAcetazolamideAcetohydroxamic AcidAcetylcholine ChlorideAcetylcysteineAcipimoxAcitretinAclidinium BromideAcotiamide hydrochlorideACP-196ActaritACTB-1003Actinomycin DACY-241AcyclovirAdapaleneAdapalene sodium saltAdefovir DipivoxilAdemetionineAdemetionine disulfate tosylateAdenineAdenine HClAdenine sulfateAdenosineAdenosine 5-monophosphateAdenosine 5'-monophosphate monohydrateAdenosine 5-triphosphateAdenosine-5'-diphosphateAdiphenine HClADL5859 HClAdoxAdrenalone HClAEE788 (NVP-AEE788)Afatinib (BIBW2992)Afatinib dimaleateAfuresertibAG-120AG-14361AG-1478AG-18AG-221 (Enasidenib)Agmatine sulfateAgomelatine-SPONSOREDAHU-377...
Sponsor A Custom Experiment Description Want to help Ora Biomedical push the limit on intervention space and work with us to design a combinatorial test with 3 or more interventions? Want to sponsor an entire library not currently available through our normal MMC sponsor page? Please let us know in the form below how you’d...
Sponsor A Random Intervention $100.00 Sponsor A Random Intervention Email * Username for leader-board (optional) I don't want the intervention to be included in the open access MMC database How did you hear about sponsoring the MMC? If you are human, leave this field blank. Add To Cart Δdocument.getElementById( "ak_js_3" ).setAttribute( "value", ( new Date()...
Sponsor an intervention $100.00 Sponsor An Intervention Intervention AbacavirAbacavir sulfateABC294640AbirateroneAbiraterone acetate - SponsoredAbscisic Acid (Dormin)ABT 702 dihydrochlorideABT-199ABT-263 (Navitoclax)-SPONSOREDABT-737ABT-751 (E7010)ABT-888 (Veliparib)AC480 (BMS-599626)Acalisib (GS-9820) Acamprosate calciumAcarbose - SponsoredAcebutolol HClAcemetacinAcesulfame PotassiumAcetaminophenAcetanilideAcetate gossypolAcetazolamideAcetohydroxamic AcidAcetylcholine ChlorideAcetylcysteineAcipimoxAcitretinAclidinium BromideAcotiamide hydrochlorideACP-196ActaritACTB-1003Actinomycin DACY-241AcyclovirAdapaleneAdapalene sodium saltAdefovir DipivoxilAdemetionineAdemetionine disulfate tosylateAdenineAdenine HClAdenine sulfateAdenosineAdenosine 5-monophosphateAdenosine 5'-monophosphate monohydrateAdenosine 5-triphosphateAdenosine-5'-diphosphateAdiphenine HClADL5859 HClAdoxAdrenalone HClAEE788 (NVP-AEE788)Afatinib (BIBW2992)Afatinib dimaleateAfuresertibAG-120AG-14361AG-1478AG-18AG-221 (Enasidenib)Agmatine sulfateAgomelatine-SPONSOREDAHU-377 hemicalcium saltAHU-377(Sacubitril)Alarelin...
When you donate to the Lifespan Extension Advocacy Foundation, you are joining the fight against our world’s number 1 killer: age-related diseases. Your donation helps us to fund breakthrough research, trustworthy news, advocacy efforts to transform public perception of longevity, and so much more.
Help Build A Healthier Future For All!Together we can end the suffering caused by age-related diseases such as cancer, heart disease, Parkinson’s, and Alzheimer’s. Donate Today Single Recurring Choose Amount $10 USD $25 USD $50 USD $100 USD $1000 USD Donate Give Per Month $10 USD/mo $25 USD/mo $50 USD/mo $100 USD/mo $1000 USD/mo Donate...
Hevolution
End of Year Fundraiser 2023: Celebrating a Year of Impact As we reflect on an extraordinary year, we can't help but feel immense gratitude and pride for what we've achieved together. The generous support from our community has fueled our mission for yet another year, allowing us to continue our work towards accelerating breakthroughs in...
Testing many longevity compounds in the million molecule challenge.
Support The Million Molecule Challenge For Longevity A moonshot project to rapidly advance longevity intervention discovery Researchers including Mitchell Lee and Matt Kaeberlein have launched the Million Molecule Challenge with Ora Biomedical. The project will rapidly screen a vast number of compounds with the potential to increase healthy longevity. The Million Molecule Challenge is seeking donors...
EARD 2023 banner.
Ending Age-Related Diseases 2023 Photos Ending Age-Related Diseases 2023 marked a return to physical conferences for Lifespan.io and what a return it was! The venue at Capitale, New York City was amazing and we had so many great guests and speakers join us. Feel free to look through the photos of the event and use...
EARD 2023
Ending Age-Related Diseases 2023 Workshops In addition to the main conference program, there will also be a selection of workshops and extra panels happening during the event. The doors open at 9am Eastern time, event starts 10am and runs until 5:30pm Eastern time. You can find the times for these below:  
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Oliver Medvedik, Ph.D.

Lifespan.io - Co-Founder / Vice President / Head of Research - Mindset

Keith Comito

Lifespan.io - President

Aubrey de Grey, Ph.D.

LEV Foundation - Founder

Christie Sacco

Lifespan.io - Social Media Manager

Steve Hill

Lifespan.io - Editor-in-Chief / Board Director

Michael Geer

Humanity - CSO

Mattijs Vonk

Lifespan.io - Marketing

Josh Conway

Lifespan.io - Editor / Journalist

Arkadi Mazin

Lifespan.io - Science Journalist

Brian Kennedy, Ph.D.

National University Singapore - Professor of Biochemistry and Physiology

Natasha Vita-More, Ph.D.

Digital University - Longevity and Evolution Expert

Steve Horvath, Ph.D.

Altos Labs - Principal Investigator San Diego Institute of Science

Vadim Gladyshev, Ph.D.

Harvard Medical School - Professor, Medicine, Harvard Medical School

Hanadie Yousef, Ph.D.

Juvena Therapeutics - CEO

Kelsey Moody, Ph.D.

Ichor Life Sciences - CEO

Michael Lustgarten, Ph.D.

Tufts University - Nutrition, Exercise Physiology, and Sarcopenia (NEPS) Team

Maria Entraigues Abramson

SENS Research Foundation

Pat Graziosi

Lifespan.io - Life Noggin

Stephanie Dainow

Lifespan.io - Executive Director

Ryan O’Shea

Lifespan.io - Lifespan News

Nathan Cheng

On Deck Longevity Biotech - Program Director

Maria Isabella

Lifespan.io - Science Journalist

Jake Mabey

Lifespan.io - Marketing

Stephen Christopher Rose

Lifespan.io - Science Journalist

Eric Morgen, M.D.

BioAge Labs - COO and Co-founder

Dylan Livingston

Alliance for Longevity Initiatives - Founder and President

Todd White

VitaDAO - Operations Steward

Fiona Miller

quadraScope - Managing Partner

Lisa Fabiny Kiser

SENS Research Foundation - CEO

Ryan McGarry

Lifespan.io - Researcher - Mindset

Matt Kaeberlein, Ph.D.

University of Washington - Professor of Laboratory Medicine and Pathology

Nir Barzilai, M.D.

Albert Einstein College of Medicine - Department of Endocrinology Medicine and the Department of Genetics

Karl Pfleger

Aging Biotech - Founder

Robert Grisham

Lifespan.io - Life Noggin

Pranav Lakherwal

Lifespan.io - Chief of Staff

Emmett Short

Lifespan.io - Lifespan News

James Hale

Lifespan.io - Partnerships Lead

Hans Keirstead, Ph.D.

Immunis Inc. - Chairman of the Board

Chauncey St. John

Angel Protocol - Founder

Jelani Clark, Ph.D.

Desci World - Core Leadership

Omar Elnagger

Weavechain - Co-Founder & CEO

Namir Khaliq

Protostellar Media - Head of creative operations

Ben Armstrong

BitBoy Crypto - Founder

Patrick Joyce, M.D.

ResearchHub - Co-Founder

Kennedy Schaal

Rejuve Bio - CEO

Anna Drangowska-Way, Ph.D.

Lifespan.io - Science Writer

Laura Minquini

AthenaDAO - Founder

Morten Scheibye-Knudsen, Ph.D.

University of Copenhagen - Group Leader

Wojciech Sierocki, M.D.

Data Lake - Co-Founder & CEO

Brian Magierski

21 Impact Labs - Founder

Joanna Bensz

Longevity Center - CEO and Founder

Michael Ringel, Ph.D.

Boston Consulting Group - Managing Director & Senior Partner

Kenneth Bogner

Montana Senate - State Senator

Eleanor Davies

VitaDAO - Longevity Dealflow

Susan Monarez, Ph.D.

ARPA-H - Deputy Director

Mahdi Moqri, Ph.D.

Stanford University - PROFESSIONAL-NX, GENETICS

J. Robertson

Próspera - VP of Development

J. Scotch McClure

Maxwell Biosciences - CEO

Maximilian Unfried, Ph.D.

National University Singapore - Researcher

Arunun Skandarajah, Ph.D.

ARPA-H - White House Presidential Innovation Fellow

Niklas Anzinger

Infinita - General Partner

Ryan Rossner, Ph.D.

Mini circle Gene Therapy Clinic - Researcher

Walter Patterson

Mini circle Gene Therapy Clinic - Co-Founder and Chief Scientific Officer

Robin Mansukhani

Deciduous Therapeutics - CEO

Deborah Duong, Ph.D.

Rejuve.AI - Chief Technology Officer

Carolina Reis Oliveira, Ph.D.

OneSkin Technology - Co-founder and CEO

Alessandra Zonari, Ph.D.

OneSkin Technology - Co-founder, CSO

Azeem Khan

Gitcoin - Head of Impact

Harry Gandhi

Lab2Market - Program Manager

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