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MitoSENS Update September 2018

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Today, we have an update from the MitoSENS team over at the SENS Research Foundation. As some of you may recall, MitoSENS was the first project we hosted on our research fundraising platform Lifespan.io back in August 2015. The project was successfully funded and raised $46,128, which was 153% of the funds needed. The extra funds were used to increase the scope of the project, which resulted in a paper being published in the prestigious Oxford Journal.

Since then, the team has been busy working on transferring the other mitochondrial genes to the nucleus, and they have given us an update to let everyone know how things are progressing at the lab. Dr. Matthew “Oki” O’Connor had the following to say about progress and the future.

Hi, everyone! Time for another exciting mito update. This time, we’ve got 2 teasers for you. The first is that we’re preparing a story about a new trick that we’ve discovered to improve the allotopic expression of mito genes. We’re still confirming that we’re 100% sure that we’re right before writing up the manuscript and making an announcement, but we’re very close. Yes, that means we’re getting it to work on more genes. Stay tuned!

The second is that we’re in the late stages of planning our first mito mouse, and we’re going to ask for your help in getting it started! This will involve combining two technologies that SENS Foundation helped invent: an advanced transgenic mouse technology and applying what we learned from the 2016 paper to a mouse model that we think will prove to the world that mito gene therapy is the future. Keep checking Lifespan.io, and you should see an announcement about the new mouse project soon.

Thanks

Oki

We are very excited about the next MitoSENS project, and we are delighted that the team at the SENS Research Foundation is going to be working with us again. The team is planning a really bold step for the MitoSENS approach, one that could possibly lead to therapies that treat mitochondrial and age-related diseases.

About the author

Steve Hill

Steve serves on the LEAF Board of Directors and is the Editor in Chief, coordinating the daily news articles and social media content of the organization. He is an active journalist in the aging research and biotechnology field and has to date written over 600 articles on the topic, interviewed over 100 of the leading researchers in the field, hosted livestream events focused on aging, as well as attending various medical industry conferences. His work has been featured in H+ magazine, Psychology Today, Singularity Weblog, Standpoint Magazine, Swiss Monthly, Keep me Prime, and New Economy Magazine. Steve is one of three recipients of the 2020 H+ Innovator Award and shares this honour with Mirko Ranieri – Google AR and Dinorah Delfin – Immortalists Magazine. The H+ Innovator Award looks into our community and acknowledges ideas and projects that encourage social change, achieve scientific accomplishments, technological advances, philosophical and intellectual visions, author unique narratives, build fascinating artistic ventures, and develop products that bridge gaps and help us to achieve transhumanist goals. Steve has a background in project management and administration which has helped him to build a united team for effective fundraising and content creation, while his additional knowledge of biology and statistical data analysis allows him to carefully assess and coordinate the scientific groups involved in the project.